Longevity & the Biology of Aging

Aging science, rapamycin, metformin, NAD, senescence, skin and appearance, and longevity frameworks.

31 episodes

~5 min read2:31:47

359 ‒ How metabolic and immune system dysfunction drive the aging process, NAD, aging clocks, & more

Eric Verdin4 Aug 202592.4K views
~5 min read2:12:32

357 ‒ A new era of longevity science: models of aging, rapamycin trials, biological clocks, & more

Brian Kennedy21 Jul 2025103.4K views
~5 min read3:10:33

355 – Skincare strategies, the science of facial aging, and cosmetic-intervention guidance

Dr. Tanuj Nakra & Dr. Suzan Obagi30 Jun 2025222.8K views
~5 min read0:45:16

342 ‒ Aging well: Peter shares strategies for improving longevity with residents at senior living

31 Mar 2025148.9K views
~4 min read2:55:00

333 ‒ Longevity roundtable—the science of aging, geroprotective molecules, & lifestyle interventions

Steven Austad, Richard Miller & Matt Kaeberlein27 Jan 2025105.2K views
~5 min read1:30:02

311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity

29 Jul 2024168.9K views
~5 min read1:48:22

300-Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, & more

6 May 2024173.7K views
~5 min read2:31:20

281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program

Richard Miller4 Dec 202374.9K views
~5 min read1:24:16

276 ‒ Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more

23 Oct 2023430.0K views
~5 min read3:01:29

272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more

David Sabatini & Matt Kaeberlein25 Sept 2023132.4K views
~4 min read2:53:27

252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting

Rhonda Patrick1 May 2023561.7K views
~4 min read1:58:07

248 ‒ OUTLIVE book: A behind-the-scenes look into the writing of this book, motivation & main themes

Bill Gifford28 Mar 202332.3K views
~4 min read1:16:17

234 ‒ Chris Hemsworth on Limitless, longevity, and happiness

Chris Hemsworth12 Dec 2022316.3K views
~4 min read2:48:00

204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.

Nir Barzilai25 Apr 2022153.3K views
~4 min read1:57:38

202 - Peter on nutrition, disease prevention, and more — looking back on the last 100 episodes

11 Apr 202250.7K views
~4 min read2:49:45

175 - The biology of aging, rapamycin, and other interventions that target the aging process

Matt Kaeberlein13 Sept 202144.4K views
~4 min read2:34:59

171- Longevity science: caloric restriction studies, aging biomarkers & possible longevity molecules

Steven Austad9 Aug 202175.1K views
~4 min read2:14:25

#148 - Richard Miller, M.D., Ph.D.: The gold standard for testing longevity drugs: the ITP

Richard Miller8 Feb 202113.1K views
~5 min read2:16:12

#123–Joan Mannick & Nir Barzilai: Rapamycin and metformin—longevity, immune enhancement, & COVID-19

Joan Mannick & Nir Barzilai10 Aug 202027.3K views
~4 min read2:14:54

#118 – Lloyd Klickstein, M.D., Ph.D.: Rapamycin, mTOR inhibition, and the biology of aging

Lloyd Klickstein9 Jul 202010.1K views
~4 min read2:15:33

#112 – Ned David, Ph.D.: How cellular senescence influences aging, and what we can do about it

Ned David8 Jul 202013.4K views
~4 min read1:17:22

#103 – Looking back on the first 99 episodes: Strong Convictions, Loosely Held

8 Jul 20202.2K views
~4 min read2:10:15

#70–David Sinclair, PhD: How cellular reprogramming could slow our aging clock, & the latest on NAD

David Sinclair14 Jan 202021.4K views
~4 min read2:27:53

#66 – Vamsi Mootha, MD: Aging, T2D, cancer, dementia, Parkinson’s—do all roads lead to mitochondria?

Vamsi Mootha13 Jan 202018.1K views
~5 min read1:55:56

#43–Alan Bauman, M.D.: The science of male and female hair restoration—how to protect & restore hair

Alan Bauman8 Jan 20206.7K views
~4 min read2:47:45

#35 – Nir Barzilai, M.D.: How to tame aging

Nir Barzilai7 Jan 202016.4K views
~4 min read2:38:45

#36 – Eric Chehab, M.D.: Extending healthspan and preserving quality of life

Eric Chehab7 Jan 20203.2K views
~4 min read1:41:32

#27 – David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging

David Sinclair6 Jan 202029.0K views
~5 min read1:48:51

#13 – Brett Kotlus, M.D.: How to look younger while we live longer

Brett Kotlus23 Dec 201916.9K views
~4 min read1:32:53

#10 – Matt Kaeberlein, Ph.D.: rapamycin and dogs — living longer, healthier & turning back the clock

Matt Kaeberlein23 Dec 20194.8K views
~4 min read1:49:49

#02 – Rhonda Patrick, Ph.D.: paradox of IGF-1, ketogenic diets and genetics, benefits of sauna, NAD+

Rhonda Patrick17 Dec 201996.4K views